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Year Number of Results
2013 1
2014 1
2015 2
2016 2
2017 3
2018 5
2019 2
2020 1
2021 4
2023 2
2024 0

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20 results

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Page 1
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, Wang K, Iyer S, Dutta C, Clendaniel V, Amaonye M, Beach A, Berth K, Biswas S, Braun MC, Chen HM, Colace TV, Ganey JD, Gangopadhyay SA, Garrity R, Kasiewicz LN, Lavoie J, Madsen JA, Matsumoto Y, Mazzola AM, Nasrullah YS, Nneji J, Ren H, Sanjeev A, Shay M, Stahley MR, Fan SHY, Tam YK, Gaudelli NM, Ciaramella G, Stolz LE, Malyala P, Cheng CJ, Rajeev KG, Rohde E, Bellinger AM, Kathiresan S. Musunuru K, et al. Among authors: denizio je. Nature. 2021 May;593(7859):429-434. doi: 10.1038/s41586-021-03534-y. Epub 2021 May 19. Nature. 2021. PMID: 34012082
Direct enzymatic sequencing of 5-methylcytosine at single-base resolution.
Wang T, Fowler JM, Liu L, Loo CE, Luo M, Schutsky EK, Berríos KN, DeNizio JE, Dvorak A, Downey N, Montermoso S, Pingul BY, Nasrallah M, Gosal WS, Wu H, Kohli RM. Wang T, et al. Among authors: denizio je. Nat Chem Biol. 2023 Aug;19(8):1004-1012. doi: 10.1038/s41589-023-01318-1. Epub 2023 Jun 15. Nat Chem Biol. 2023. PMID: 37322153 Free PMC article.
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.
Fraietta JA, Nobles CL, Sammons MA, Lundh S, Carty SA, Reich TJ, Cogdill AP, Morrissette JJD, DeNizio JE, Reddy S, Hwang Y, Gohil M, Kulikovskaya I, Nazimuddin F, Gupta M, Chen F, Everett JK, Alexander KA, Lin-Shiao E, Gee MH, Liu X, Young RM, Ambrose D, Wang Y, Xu J, Jordan MS, Marcucci KT, Levine BL, Garcia KC, Zhao Y, Kalos M, Porter DL, Kohli RM, Lacey SF, Berger SL, Bushman FD, June CH, Melenhorst JJ. Fraietta JA, et al. Among authors: denizio je. Nature. 2018 Jun;558(7709):307-312. doi: 10.1038/s41586-018-0178-z. Epub 2018 May 30. Nature. 2018. PMID: 29849141 Free PMC article.
Tuning Hsp104 specificity to selectively detoxify α-synuclein.
Mack KL, Kim H, Barbieri EM, Lin J, Braganza S, Jackrel ME, DeNizio JE, Yan X, Chuang E, Tariq A, Cupo RR, Castellano LM, Caldwell KA, Caldwell GA, Shorter J. Mack KL, et al. Among authors: denizio je. Mol Cell. 2023 Sep 21;83(18):3314-3332.e9. doi: 10.1016/j.molcel.2023.07.029. Epub 2023 Aug 24. Mol Cell. 2023. PMID: 37625404
The expanding scope and impact of epigenetic cytosine modifications.
Liu MY, DeNizio JE, Schutsky EK, Kohli RM. Liu MY, et al. Among authors: denizio je. Curr Opin Chem Biol. 2016 Aug;33:67-73. doi: 10.1016/j.cbpa.2016.05.029. Epub 2016 Jun 14. Curr Opin Chem Biol. 2016. PMID: 27315338 Free PMC article. Review.
TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites.
DeNizio JE, Dow BJ, Serrano JC, Ghanty U, Drohat AC, Kohli RM. DeNizio JE, et al. J Mol Biol. 2021 Apr 16;433(8):166877. doi: 10.1016/j.jmb.2021.166877. Epub 2021 Feb 7. J Mol Biol. 2021. PMID: 33561435 Free PMC article.
20 results